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Literature summary extracted from

  • Ellis, G.; Goldberg, D.M.
    Galactose-1-phosphate uridylytransferase. UDPglucose:alpha-D-galactose-1-phosphate uridylyltransferase, EC 2.7.7.12 (1983), Methods Enzym. Anal. , 3rd. Ed. (Bergmeyer, H. U. , ed. ), 3, 560-571.
No PubMed abstract available

General Stability

EC Number General Stability Organism
2.7.7.12 sulfhydryl reagents restore activity of partially denatured enzyme and protect against inactivation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.12 ADP erythrocytes Homo sapiens
2.7.7.12 alpha-D-glucose 1-phosphate erythrocytes Homo sapiens
2.7.7.12 ATP erythrocytes Homo sapiens
2.7.7.12 Cl-
-
 Bos taurus
2.7.7.12 Cl-
-
 Homo sapiens
2.7.7.12 D-glucose 6-phosphate erythrocytes Homo sapiens
2.7.7.12 diethyldicarbonate erythrocytes Homo sapiens
2.7.7.12 iodoacetate erythrocytes Homo sapiens
2.7.7.12 PCMB erythrocytes Homo sapiens
2.7.7.12 UDP
-
 Bos taurus
2.7.7.12 UDP-glucose product inhibition Bos taurus
2.7.7.12 UDP-glucose product inhibition Homo sapiens
2.7.7.12 UMP
-
 Bos taurus
2.7.7.12 UTP
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.12 Bos taurus
-
 calf
-
2.7.7.12 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.12 erythrocyte
-
 Homo sapiens
-
2.7.7.12 leukocyte
-
 Homo sapiens
-
2.7.7.12 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.12 UDP-glucose + alpha-D-galactose 1-phosphate
-
 Homo sapiens alpha-D-glucose 1-phosphate + UDP-galactose
-
 r
2.7.7.12 UDP-glucose + alpha-D-galactose 1-phosphate
-
 Bos taurus alpha-D-glucose 1-phosphate + UDP-galactose
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.12 8.7
-
 erythrocytes Homo sapiens