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Literature summary extracted from

  • Kono, M.; Shimizu, C.; Matsui, T.; Matsuura, F.
    Purification of NAD pyrophosphorylase from muscle of skipjack and its properties (1978), Nippon Suisan Gakkaishi, 44, 379-384.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.7.1 beta-naphthoquinone 4-sulfonate strong Katsuwonus pelamis
2.7.7.1 Metal ions strong, Mg2+, Ni2+ or Co2+ activates Katsuwonus pelamis
2.7.7.1 N-bromosuccinimide strong Katsuwonus pelamis

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.7.1 0.08
-
 nicotinate D-ribonucleotide nicotinamide ribonucleotide Katsuwonus pelamis
2.7.7.1 0.11
-
 ATP
-
 Katsuwonus pelamis
2.7.7.1 0.22
-
 diphosphate
-
 Katsuwonus pelamis
2.7.7.1 0.25
-
 NAD+
-
 Katsuwonus pelamis

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.7.1 nucleus
-
 Katsuwonus pelamis 5634
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.7.1 Co2+
-
 Katsuwonus pelamis
2.7.7.1 divalent cations requirement, particularly Mg2+, Co2+ and Ni2+, strong inhibition by some metal ions Katsuwonus pelamis
2.7.7.1 Mg2+ requirement Katsuwonus pelamis
2.7.7.1 Mn2+
-
 Katsuwonus pelamis
2.7.7.1 Ni2+
-
 Katsuwonus pelamis
2.7.7.1 Zn2+
-
 Katsuwonus pelamis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.7.1 200000
-
 gel filtration Katsuwonus pelamis

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.7.1 ATP + nicotinamide ribonucleotide Katsuwonus pelamis
-
 diphosphate + NAD+
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.7.1 Katsuwonus pelamis
-
 skipjack tuna
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.7.1 muscle
-
 Katsuwonus pelamis
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.7.1 ATP + nicotinamide ribonucleotide
-
 Katsuwonus pelamis diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinamide ribonucleotide i.e. NMN or nicotinamide mononucleotide Katsuwonus pelamis diphosphate + NAD+
-
 r
2.7.7.1 ATP + nicotinate D-ribonucleotide
-
 Katsuwonus pelamis diphosphate + deamino-NAD+
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.7.1 7 10 broad Katsuwonus pelamis

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.7.1 Katsuwonus pelamis
-
-
 4.2