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Literature summary extracted from

  • Jones, G.H.
    Purification and properties of ATP:GTP 3-pyrophosphotransferase (guanosine pentaphosphate synthetase) from Streptomyces antibioticus (1994), J. Bacteriol., 176, 1475-1481.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.6.5 47000
-
 1 * 47000, GPS II, produced by proteolysis of the larger 88000 MW form, denaturing PAGE, 1 * 88000, GPS I, denaturing PAGE Streptomyces antibioticus
2.7.6.5 88000
-
 1 * 47000, GPS II, produced by proteolysis of the larger 88000 MW form, denaturing PAGE, 1 * 88000, GPS I, denaturing PAGE Streptomyces antibioticus

Organism

EC Number Organism UniProt Comment Textmining
2.7.6.5 Saccharopolyspora erythraea
-
-
-
2.7.6.5 Streptomyces albus
-
 ATCC 21828
-
2.7.6.5 Streptomyces ambofaciens
-
 ATCC 15155
-
2.7.6.5 Streptomyces antibioticus
-
 2 enzyme forms: GPS I
-
2.7.6.5 Streptomyces antibioticus
-
 GPS II
-
2.7.6.5 Streptomyces anulatus
-
 ATCC 11523
-
2.7.6.5 Streptomyces coelicolor
-
 A3
-
2.7.6.5 Streptomyces fradiae
-
 UC8306
-
2.7.6.5 Streptomyces fradiae UC8306
-
 UC8306
-
2.7.6.5 Streptomyces glaucescens
-
 ETH 22794
-
2.7.6.5 Streptomyces glaucescens ETH 22794
-
 ETH 22794
-
2.7.6.5 Streptomyces lividans
-
 TK24
-
2.7.6.5 Streptomyces lividans TK24
-
 TK24
-
2.7.6.5 Streptomyces parvulus
-
 ATCC 12434
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.6.5
-
 Streptomyces antibioticus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.6.5 mycelium
-
 Streptomyces coelicolor
-
2.7.6.5 mycelium
-
 Streptomyces albus
-
2.7.6.5 mycelium
-
 Streptomyces fradiae
-
2.7.6.5 mycelium
-
 Streptomyces glaucescens
-
2.7.6.5 mycelium
-
 Saccharopolyspora erythraea
-
2.7.6.5 mycelium
-
 Streptomyces lividans
-
2.7.6.5 mycelium
-
 Streptomyces antibioticus
-
2.7.6.5 mycelium
-
 Streptomyces parvulus
-
2.7.6.5 mycelium
-
 Streptomyces anulatus
-
2.7.6.5 mycelium
-
 Streptomyces ambofaciens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.6.5 1.14
-
-
 Streptomyces antibioticus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.6.5 ATP + GTP
-
 Streptomyces coelicolor AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces albus AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces fradiae AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces glaucescens AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Saccharopolyspora erythraea AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces lividans AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces antibioticus AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces parvulus AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces anulatus AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces ambofaciens AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces fradiae UC8306 AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces glaucescens ETH 22794 AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?
2.7.6.5 ATP + GTP
-
 Streptomyces lividans TK24 AMP + guanosine 3'-diphosphate 5'-triphosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.6.5 monomer 1 * 47000, GPS II, produced by proteolysis of the larger 88000 MW form, denaturing PAGE, 1 * 88000, GPS I, denaturing PAGE Streptomyces antibioticus