Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Mitsuda, H.; Takii, Y.; Iwami, K.; Yasumoto, K.
    Mechanism and regulation of thiamine pyrophosphokinase from parsely leaf (1975), J. Nutr. Sci. Vitaminol., 21, 189-198.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.6.2 diphosphate competitive with respect to thiamine Petroselinum crispum
2.7.6.2 Thiamine monophosphate
-
 Petroselinum crispum

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.6.2 2.9
-
 thiamine
-
 Petroselinum crispum
2.7.6.2 4.5
-
 ATP ATP in form of MgATP2- Petroselinum crispum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.6.2 Co2+ absolute requirement for a divalent cation such as Mg2+, Mn2+ or Co2+. In presence of 2 mM ATP maximal activity occurs with 1 mM Co2+ Petroselinum crispum
2.7.6.2 Mg2+ absolute requirement for a divalent cation such as Mg2+, Mn2+ or Co2+. In presence of 2 mM ATP maximal activity occurs with above 3 mM Mg2+ Petroselinum crispum
2.7.6.2 Mn2+ absolute requirement for a divalent cation such as Mg2+, Mn2+ or Co2+. In presence of 2 mM ATP maximal activity occurs with 0.5 mM Mn2+ Petroselinum crispum

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.6.2 30000
-
 gel filtration Petroselinum crispum

Organism

EC Number Organism UniProt Comment Textmining
2.7.6.2 Petroselinum crispum
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.6.2 leaf
-
 Petroselinum crispum
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.6.2 ATP + thiamine
-
 Petroselinum crispum AMP + thiamine diphosphate
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.6.2 0.2
-
 Thiamine monophosphate
-
 Petroselinum crispum
2.7.6.2 2.8
-
 diphosphate
-
 Petroselinum crispum