EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.4.21 | expression in Escherichia coli | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.4.21 | 0.0009 | - |
Inositol hexakisphosphate | pH 7.0, 37°C | Homo sapiens | |
2.7.4.21 | 0.0055 | - |
D-myo-inositol-1,3,4,5,6-pentakisphosphate | pH 7.0, 37°C | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.4.21 | cytoplasm | predominate in cytoplasm with only modest nuclear levels | Homo sapiens | 5737 | - |
2.7.4.21 | cytoplasm | comparable amounts of activity in the nucleus and cytoplasm | Mus musculus | 5737 | - |
2.7.4.21 | cytoplasmic vesicle | low level of activity | Homo sapiens | 31410 | - |
2.7.4.21 | nucleus | predominate in cytoplasm with only modest nuclear levels | Homo sapiens | 5634 | - |
2.7.4.21 | nucleus | comparable amounts of activity in the nucleus and cytoplasm | Mus musculus | 5634 | - |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.4.21 | Homo sapiens | Q96PC2 | - |
- |
2.7.4.21 | Mus musculus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.4.21 | brain | - |
Homo sapiens | - |
2.7.4.21 | cerebellum | - |
Mus musculus | - |
2.7.4.21 | cerebellum | highest activity occurs in Purkinje cells with somewhat lower levels in granule cells. In hippocampus substantial densities occur in CA1-CA4 layers of the hippocampus as well as the dentate gyrus | Homo sapiens | - |
2.7.4.21 | hippocampus | - |
Homo sapiens | - |
2.7.4.21 | kidney | moderate activity | Homo sapiens | - |
2.7.4.21 | neuron | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.4.21 | ATP + 1D-myo-inositol hexakisphosphate | - |
Mus musculus | ADP + 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate | - |
? | |
2.7.4.21 | ATP + 1D-myo-inositol hexakisphosphate | - |
Homo sapiens | ADP + 5-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate | - |
? | |
2.7.4.21 | ATP + 1D-myo-inositol-1,3,4,5,6-pentakisphosphate | - |
Homo sapiens | ADP + diphospho-1D-myo-inositol tetrakisphosphate | - |
? |