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Literature summary extracted from

  • Pradel, L.A.; Kassab, R.; van Thoai, N.
    On ATP:guanidinoacetate N-phosphotransferase (1964), Biochim. Biophys. Acta, 81, 86-95.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.3.1 Chloroacetophenone
-
 Nephtys caeca
2.7.3.1 iodoacetic acid
-
 Nephtys caeca
2.7.3.1 N-ethylmaleimide
-
 Nephtys caeca
2.7.3.1 NH2OH
-
 Nephtys caeca
2.7.3.1 p-chloromercuribenzoate
-
 Nephtys caeca
2.7.3.1 phenylhydrazine inhibits phosphorylation of ADP Nephtys caeca

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.3.1 0.33
-
 Guanidinoacetate
-
 Nephtys caeca
2.7.3.1 3.3
-
 ATP
-
 Nephtys caeca
2.7.3.1 6.8
-
 phosphoguanidinoacetate
-
 Nephtys caeca
2.7.3.1 10
-
 ADP
-
 Nephtys caeca

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.3.1 Ca2+ slightly Nephtys caeca
2.7.3.1 Mg2+
-
 Nephtys caeca
2.7.3.1 Mn2+
-
 Nephtys caeca

Organism

EC Number Organism UniProt Comment Textmining
2.7.3.1 Nephtys caeca
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.3.1 muscle
-
 Nephtys caeca
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.3.1 ADP + phosphocreatine poor substrate Nephtys caeca ATP + ?
-
 ?
2.7.3.1 ADP + phosphoguanidinoacetate
-
 Nephtys caeca ATP + guanidinoacetate
-
 ?
2.7.3.1 ATP + guanidinoacetate not: arginine, creatine, lombricine Nephtys caeca ADP + phosphoguanidinoacetate
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.3.1 22
-
 phosphorylation of guanidinoacetate Nephtys caeca
2.7.3.1 40
-
 optimum above, phosphorylation of ADP Nephtys caeca

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.7.3.1 16 32 less than 50% of maximal activity above and below, phosphorylation of guanidinoacetate Nephtys caeca

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.3.1 6.8
-
 phosphorylation of ADP Nephtys caeca
2.7.3.1 8.9
-
 phosphorylation of guanidinoacetate Nephtys caeca