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Literature summary extracted from

  • Saiki, T.; Yamazumi, K.; Arima, K.
    Aspartokinase of an extreme thermophile Thermus flavus partial purification and some properties (1977), Agric. Biol. Chem., 41, 1651-1655.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.2.4 L-threonine
-
 Thermus thermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.2.4 ATP + L-aspartate Thermus thermophilus
-
 ADP + 4-phospho-L-aspartate
-
 r
2.7.2.4 ATP + L-aspartate Thermus thermophilus AT-62
-
 ADP + 4-phospho-L-aspartate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.4 Thermus thermophilus
-
 AT-62
-
2.7.2.4 Thermus thermophilus AT-62
-
 AT-62
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.2.4 partial Thermus thermophilus

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.2.4 58.6
-
-
 Thermus thermophilus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.4 ATP + L-aspartate
-
 Thermus thermophilus ADP + 4-phospho-L-aspartate
-
 r
2.7.2.4 ATP + L-aspartate
-
 Thermus thermophilus AT-62 ADP + 4-phospho-L-aspartate
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.2.4 75
-
-
 Thermus thermophilus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
2.7.2.4 40 80
-
 Thermus thermophilus

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.7.2.4 70 85 very heat stable, not inactivated after 30 min at 70°C, 30% of the original activity is lost after 30 min at 80°C, rapid inactivation above 85°C Thermus thermophilus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.2.4 7 8
-
 Thermus thermophilus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.7.2.4 5.5 10
-
 Thermus thermophilus

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.7.2.4 5.5 10 stable at slight alkali to acidic pH range, most stable at about pH 7.0, unstable at high alkali pH range, losing 90% of its original activity after 30 min at 70°C at pH 10.0 Thermus thermophilus