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Literature summary extracted from

  • Yoshida, A.; Watanabe, S.; Chen, S.H.; Giblett, E.R.; Malcolm, L.A.
    Human phosphoglycerate kinase. II. Structure of a variant enzyme (1972), J. Biol. Chem., 247, 446-449.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.7.2.3
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.2.3 50000
-
 sedimentation equilibrium method Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.2.3 Homo sapiens
-
 New Guinea human variant
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.2.3 variants of humans in New Guinea and a male in the Samoa Islands Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.2.3 blood
-
 Homo sapiens
-
2.7.2.3 erythrocyte
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.2.3 700
-
 purified New Guinea variant Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.2.3 ATP + 3-phospho-D-glycerate
-
 Homo sapiens ADP + 1,3-diphosphoglycerate
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.2.3 25
-
 assay at Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.2.3 ADP
-
 Homo sapiens
2.7.2.3 ATP required as phosphate donor Homo sapiens

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.2.3 Homo sapiens New Guinea population variant, isoelectric focusing 4.8 4.7