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Literature summary extracted from

  • Kim, M.Y.; Ikeda, S.; Ives, D.H.
    Affinity purification of human deoxycytidine kinase: avoidance of structural and kinetic artifacts arising from limited proteolysis (1988), Biochem. Biophys. Res. Commun., 156, 92-98.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.74 0.0033 0.0093 deoxycytidine
-
 Homo sapiens
2.7.1.74 0.64
-
 deoxyguanosine 37°C, pH 7.5 Homo sapiens
2.7.1.74 0.89
-
 deoxyadenosine 37°C, pH 7.5 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.74 59300
-
 sedimentation equilibrium determination, PAGE, both in the presence of protease inhibitors Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.74 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.74 affinity chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.74 leukemia cell leukemic T-lymphoblasts Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.74 ATP + 2'-deoxycytidine
-
 Homo sapiens ADP + 5'-dCMP
-
 ?
2.7.1.74 CTP + 2'-deoxycytidine
-
 Homo sapiens CDP + 2'-deoxy-CMP
-
 ?
2.7.1.74 dGTP + 2'-deoxycytidine
-
 Homo sapiens dGDP + 2'-deoxy-CMP
-
 ?
2.7.1.74 dTTP + 2'-deoxycytidine
-
 Homo sapiens dTDP + 2'-deoxy-CMP
-
 ?
2.7.1.74 GTP + 2'-deoxycytidine
-
 Homo sapiens GDP + 2'-deoxy-CMP
-
 ?
2.7.1.74 additional information purine deoxynucleoside activity inseparably associated with deoxycytidine kinase protein Homo sapiens ?
-
 ?
2.7.1.74 NTP + deoxyadenosine
-
 Homo sapiens NDP + dAMP
-
 ?
2.7.1.74 NTP + deoxycytidine no substrate: dCTP Homo sapiens NDP + dCMP
-
 ?
2.7.1.74 NTP + deoxyguanosine
-
 Homo sapiens NDP + dGMP
-
 ?
2.7.1.74 UTP + 2'-deoxycytidine
-
 Homo sapiens UDP + 2'-deoxy-CMP
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.1.74 monomer
-
 Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.74 37
-
 assay at Homo sapiens