BRENDA - Enzyme Database

Phosphatidic acid is a specific activator of phosphatidylinositol-4-phosphate kinase

Moritz, A.; De Graan, P.N.E.; Gispen, W.H.; Wirtz, K.W.A.; J. Biol. Chem. 267, 7207-7210 (1992)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.1.68
phosphatidic acid
stimulates in a concentration-dependent manner up to 20fold when an equal molar ratio of phosphatidic acid to phosphatidylinositol 4-phosphate is attained
Bos taurus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.1.68
membrane
-
Bos taurus
16020
-
2.7.1.68
plasma membrane
synaptosomal plasma membrane
Bos taurus
5886
-
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.1.68
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
Bos taurus
the enzyme may be under control of phosphatidic acid level in membranes
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.1.68
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.1.68
brain
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.68
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
641835
Bos taurus
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
-
-
?
2.7.1.68
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
the enzyme may be under control of phosphatidic acid level in membranes
641835
Bos taurus
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
-
-
-
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.1.68
phosphatidic acid
stimulates in a concentration-dependent manner up to 20fold when an equal molar ratio of phosphatidic acid to phosphatidylinositol 4-phosphate is attained
Bos taurus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.1.68
membrane
-
Bos taurus
16020
-
2.7.1.68
plasma membrane
synaptosomal plasma membrane
Bos taurus
5886
-
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.1.68
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
Bos taurus
the enzyme may be under control of phosphatidic acid level in membranes
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.1.68
brain
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.68
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
641835
Bos taurus
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
-
-
?
2.7.1.68
ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
the enzyme may be under control of phosphatidic acid level in membranes
641835
Bos taurus
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate
-
-
-
-