Literature summary extracted from

Flynn, I.W.; Bowman, I.B.R.
Some kinetic properties of pyruvate kinase from Trypanosoma brucei: influence of pH and fructose-1,6-diphosphate (1981), Mol. Biochem. Parasitol., 4, 95-106.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.1.40	D-fructose 1,6-diphosphate	activation	Trypanosoma brucei
2.7.1.40	D-fructose 1,6-diphosphate	allosteric activation together with phosphoenolpyruvate	Trypanosoma brucei

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.7.1.40	additional information	-	additional information	kinetic properties	Trypanosoma brucei
2.7.1.40	additional information	-	additional information	pH-dependence	Trypanosoma brucei

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.7.1.40	Na+	activation, can replace K+	Trypanosoma brucei

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.40	Trypanosoma brucei	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.40	ADP + phosphoenolpyruvate	-	Trypanosoma brucei	ATP + pyruvate	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)