Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Storey, K.
    Kinetic and regulatory properties of pyruvate kinase isozymes from flight muscle and fat body of the cockroach, Periplaneta americana (1985), J. Comp. Physiol. B, 155, 339-345.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.40 D-fructose 1,6-diphosphate activation Periplaneta americana
2.7.1.40 D-fructose 1,6-diphosphate not Periplaneta americana
2.7.1.40 D-fructose 1,6-diphosphate strong activation, fat body enzyme Periplaneta americana

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.40 arginine phosphate flight muscle isozyme: weak; fructose 1,6-diphosphate restores Periplaneta americana
2.7.1.40 citrate fat body isozyme; weak, flight muscle isozyme Periplaneta americana
2.7.1.40 L-alanine weak; weak, flight muscle isozyme Periplaneta americana

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.40 0.04 0.063 phosphoenolpyruvate
-
 Periplaneta americana
2.7.1.40 0.2 0.35 ADP
-
 Periplaneta americana

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.40 K+ activation Periplaneta americana
2.7.1.40 Mg2+ Km-value: 0.8 mM Periplaneta americana
2.7.1.40 Mn2+ Km-value: 0.6 mM, flight muscle isozyme Periplaneta americana

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.1.40 235000
-
-
 Periplaneta americana

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.40 Periplaneta americana
-
 cockroach
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.40 2 isozymes, in flight muscle and fat body Periplaneta americana

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.40 fat body
-
 Periplaneta americana
-
2.7.1.40 muscle flight muscle Periplaneta americana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.40 ADP + phosphoenolpyruvate
-
 Periplaneta americana ATP + pyruvate
-
 ?

pI Value

EC Number Organism Comment pI Value Maximum pI Value
2.7.1.40 Periplaneta americana flight muscle isozyme
-
 5.75
2.7.1.40 Periplaneta americana fat body isozyme
-
 6.15