Literature summary extracted from

Zhou, T.; Daugherty, M.; Grishin, N.V.; Osterman, A.L.; Zhang, H.
Structure and mechanism of homoserine kinase: prototype for the GHMP kinase superfamily (2000), Structure Fold. Des., 8, 1247-1257.

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.7.1.39	crystal structure of the enzyme with ADP reveals a novel nucleotide binding fold. The N-terminal domain contains an unusual left-handed beta,alpha,beta unit, while the C-terminal domain has a central alpha-beta plait fold with an insertion of four helices	Methanocaldococcus jannaschii
2.7.1.39	crystals are grown by the hanging drop vapor diffusion method	Methanocaldococcus jannaschii

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.39	Methanocaldococcus jannaschii	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.39	ATP + L-homoserine	-	Methanocaldococcus jannaschii	ADP + O-phospho-L-homoserine	-	?

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Release 2023.1 (January 2023)