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Literature summary extracted from

  • Rowen, J.W.; Kornberg, A.
    The phosphorolysis of nicotinamide riboside (1951), J. Biol. Chem., 193, 497-507.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.22 0.28
-
 phosphate pH 7.4 Sus scrofa
2.7.1.22 1.1
-
 nicotinamide riboside pH 7.4 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.22 Sus scrofa
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.22 ammonium sulfate, calcium phosphate gel, alumina gel Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.22 liver
-
 Sus scrofa
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.1.22 4.25
-
-
 Sus scrofa

Storage Stability

EC Number Storage Stability Organism
2.7.1.22 -10°C, several weeks, no loss of activity Sus scrofa

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.22 ATP + N-ribosylnicotinamide
-
 Sus scrofa ADP + nicotinamide ribonucleotide
-
 ?
2.7.1.22 phosphate + inosine
-
 Sus scrofa ?
-
 ?
2.7.1.22 phosphate + nicotinamide riboside
-
 Sus scrofa nicotinamide + ribose-1-phosphate
-
 r

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.22 8
-
 nicotinamide riboside phosphorolysis Sus scrofa

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.7.1.22 6 10 approx. 25% of maximal activity at pH 6.0, approx. 55% of maximal activity at pH 10, nicotinamide riboside phosphorolysis Sus scrofa