EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.21 | 5-bromodeoxyuridine | competitive to thymidine | Physarum polycephalum | |
2.7.1.21 | 5-fluorodeoxyuridine | competitive to thymidine | Physarum polycephalum | |
2.7.1.21 | 5-iododeoxyuridine | competitive to thymidine | Physarum polycephalum | |
2.7.1.21 | ADP | competitive to ATP | Physarum polycephalum | |
2.7.1.21 | Caffeine | competitive to ATP | Physarum polycephalum | |
2.7.1.21 | deoxyuridine | - |
Physarum polycephalum | |
2.7.1.21 | dGDP | competitive to ATP | Physarum polycephalum | |
2.7.1.21 | dTDP | competitive to ATP | Physarum polycephalum | |
2.7.1.21 | dTMP | competitive to ATP | Physarum polycephalum | |
2.7.1.21 | dTTP | non-competitive with thymidine, competitive to ATP | Physarum polycephalum | |
2.7.1.21 | dUTP | competitive to ATP | Physarum polycephalum |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.21 | additional information | - |
additional information | - |
Physarum polycephalum |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.21 | Mg2+ | 7.5-10 mM, required | Physarum polycephalum |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.21 | Physarum polycephalum | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.21 | - |
Physarum polycephalum |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.21 | plasmodium | - |
Physarum polycephalum | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.1.21 | 100 | - |
- |
Physarum polycephalum |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.21 | ATP + thymidine | ATP can be substituted by dATP | Physarum polycephalum | ADP + dTMP | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.21 | 7.5 | 9 | - |
Physarum polycephalum |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
2.7.1.21 | 7 | 9.5 | less than 70% of maximal activity above and below | Physarum polycephalum |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.21 | 0.001 | 0.0045 | 5-iododeoxyuridine | pH 7.5, 27°C | Physarum polycephalum | |
2.7.1.21 | 0.0015 | 0.0055 | 5-bromodeoxyuridine | pH 7.5, 27°C | Physarum polycephalum | |
2.7.1.21 | 0.014 | 0.036 | dTTP | pH 7.5, 27°C | Physarum polycephalum | |
2.7.1.21 | 0.06 | 0.096 | 5-fluorodeoxyuridine | pH 7.5, 27°C | Physarum polycephalum | |
2.7.1.21 | 0.27 | 1.54 | deoxyuridine | pH 7.5, 27°C | Physarum polycephalum | |
2.7.1.21 | 0.5 | 0.65 | dTDP | pH 7.5, 27°C | Physarum polycephalum | |
2.7.1.21 | 3.6 | 4.7 | dTMP | pH 7.5, 27°C | Physarum polycephalum |