EC Number | General Stability | Organism |
---|---|---|
2.7.1.21 | bovine serum albumin, 0.5 mg/ml stabilizes | Homo sapiens |
2.7.1.21 | dithiothreitol essential for stability | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.21 | dCTP | mitochondrial enzyme | Homo sapiens | |
2.7.1.21 | dTTP | - |
Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.21 | 0.0026 | - |
thymidine | cytoplasmic enzyme, pH 7.5, 37°C | Homo sapiens | |
2.7.1.21 | 0.003 | - |
deoxycytidine | mitochondrial enzyme, pH 7.5, 37°C | Homo sapiens | |
2.7.1.21 | 0.005 | 0.0052 | thymidine | mitochondrial enzyme, pH 7.5, 37°C | Homo sapiens | |
2.7.1.21 | 0.1 | - |
ATP | mitochondrial enzyme, pH 7.5, 37°C | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.7.1.21 | cytoplasm | - |
Homo sapiens | 5737 | - |
2.7.1.21 | mitochondrion | - |
Homo sapiens | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
2.7.1.21 | Ca2+ | can partially substitute for Mg2+ | Homo sapiens | |
2.7.1.21 | Cu2+ | can partially substitute for Mg2+ | Homo sapiens | |
2.7.1.21 | Fe2+ | can partially substitute for Mg2+ | Homo sapiens | |
2.7.1.21 | Mg2+ | - |
Homo sapiens | |
2.7.1.21 | Mn2+ | can partially substitute for Mg2+ | Homo sapiens | |
2.7.1.21 | Zn2+ | can partially substitute for Mg2+ | Homo sapiens |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.21 | 70000 | 74000 | mitochondria, glycerol gradient centrifugation | Homo sapiens |
2.7.1.21 | 84000 | 98000 | cytoplasm, glycerol density gradient centrifugation | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.21 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.7.1.21 | rLyTK1Val-106 and rLyTK1Met-106 | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.21 | blast cell | - |
Homo sapiens | - |
EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|---|
2.7.1.21 | additional information | - |
- |
Homo sapiens |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.21 | ATP + 2'-deoxycytidine | - |
Homo sapiens | ADP + 2'-deoxycytidine 5'-phosphate | - |
? | |
2.7.1.21 | ATP + 5-bromo-2'-deoxyuridine | - |
Homo sapiens | ADP + 5-bromo-2'-deoxyuridine 5'-phosphate | - |
? | |
2.7.1.21 | ATP + 5-iodo-2'-deoxyuridine | - |
Homo sapiens | ADP + 5-iodo-2'-deoxyuridine 5'-phosphate | - |
? | |
2.7.1.21 | ATP + thymidine | ATP can be substituted by dATP | Homo sapiens | ADP + dTMP | - |
? |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.7.1.21 | 0.002 | - |
dCTP | pH 7.5, 37°C | Homo sapiens | |
2.7.1.21 | 0.01 | - |
dTTP | pH 7.5, 37°C | Homo sapiens |