Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Maj, M.; Singh, B.; Gupta, R.S.
    The influence of inorganic phosphate on the activity of adenosine kinase (2000), Biochim. Biophys. Acta, 1476, 33-42.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.20 phosphate the degree of dependence varies among enzyme source and pH. At pH 6.2, complete dependence Cricetulus griseus
2.7.1.20 phosphate the degree of dependence varies among enzyme source and pH. At pH 6.2, complete dependence Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.20 adenosine
-
Bos taurus
2.7.1.20 adenosine
-
Cricetulus griseus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.20 0.7 6.4 adenosine affinity increases asymptotically upon the addition of increasing phosphate from 1 to 50 mM Cricetulus griseus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.20 Bos taurus
-
beef
-
2.7.1.20 Cricetulus griseus
-
chinese hamster
-
2.7.1.20 Cricetulus griseus
-
CHO cells
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.20 CHO cell
-
Cricetulus griseus
-
2.7.1.20 liver beef Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.20 ATP + adenosine
-
Cricetulus griseus ADP + AMP
-
?
2.7.1.20 ATP + adenosine
-
Bos taurus ADP + AMP
-
?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.20 7.4
-
higher affinity for adenosine and lower sensitivity to substrate inhibition in the presence of phosphate Cricetulus griseus
2.7.1.20 7.4
-
higher affinity for adenosine and lower sensitivity to substrate inhibition in the presence of phosphate Bos taurus