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Literature summary extracted from

  • Mimouni, M.; Bontemps, F.; Van den Berghe, G.
    Kinetic studies of rat liver adenosine kinase. Explanation of exchange reaction between adenosine and AMP (1994), J. Biol. Chem., 269, 17820-17825.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.20 ADP product inhibition Rattus norvegicus
2.7.1.20 AMP product inhibition Rattus norvegicus
2.7.1.20 EDTA at 100 mM Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.20 additional information
-
 additional information kinetic study Rattus norvegicus
2.7.1.20 0.00012
-
 adenosine pH 7.2, 37ºC Rattus norvegicus
2.7.1.20 0.00015 0.0005 adenosine pH 7.2, 37ºC Rattus norvegicus
2.7.1.20 0.003
-
 ADP pH 7.2, 37ºC Rattus norvegicus
2.7.1.20 0.014
-
 MgATP2- pH 7.2, 37ºC Rattus norvegicus
2.7.1.20 0.016
-
 AMP pH 7.2, 37ºC Rattus norvegicus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.20 Mg2+ activation Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.20 Rattus norvegicus
-
 male, Wistar strain
-
2.7.1.20 Rattus norvegicus Wistar
-
 male, Wistar strain
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.20
-
 Rattus norvegicus

Reaction

EC Number Reaction Comment Organism Reaction ID
2.7.1.20 ATP + adenosine = ADP + AMP mechanism Rattus norvegicus
a
2.7.1.20 ATP + adenosine = ADP + AMP ordered bi bi mechanism Rattus norvegicus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.20 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.20 ATP + 2'-deoxy-adenosine
-
 Rattus norvegicus ADP + 2'-deoxy-AMP
-
 ?
2.7.1.20 ATP + 2'-deoxy-adenosine
-
 Rattus norvegicus Wistar ADP + 2'-deoxy-AMP
-
 ?
2.7.1.20 ATP + adenosine
-
 Rattus norvegicus ADP + AMP
-
 ?
2.7.1.20 ATP + adenosine
-
 Rattus norvegicus Wistar ADP + AMP
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.20 37
-
 assay at Rattus norvegicus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.1.20 0.011
-
 ADP pH 7.2, 37ºC, with variable MgATP2- and constant adenosine concentrations Rattus norvegicus
2.7.1.20 0.16
-
 AMP pH 7.2, 37ºC, with constant MgATP2- and variable adenosine concentrations Rattus norvegicus