Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Misawa, H.; Ohtsubo, M.; Copeland, N.G.; Gilbert, D.J.; Jenkins, N.A.; Yoshimura, A.
    Cloning and characterization of a novel class II phosphoinositide 3-kinase containing C2 domain (1998), Biochem. Biophys. Res. Commun., 244, 531-539.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.137 PI3K-C2 gamma gene locus is mapped to the distal region of mouse chromosome 6 in a region of homology with human chromosome 12p Mus musculus
2.7.1.154
-
 Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.154 Wortmannin
-
 Mus musculus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.137 Mus musculus O70167
-
-
2.7.1.154 Mus musculus O70167 PI3-C2gamma
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.137 cell culture a N-terminal truncated form is found a certain hematopoietic cell line Mus musculus
-
2.7.1.137 liver
-
 Mus musculus
-
2.7.1.137 lung a N-terminal truncated form is found in lung Mus musculus
-
2.7.1.154 liver exclusively expressed in liver Mus musculus
-
2.7.1.154 lymphoid cell
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidylinositol
-
 Mus musculus ADP + phosphatidylinositol 3-phosphate
-
 ?