Literature summary extracted from

Velloso, L.A.; Carvalho, C.R.O.; Rojas, F.A.; Folli, F.; Saad, M.J.A.
Insulin signaling in heart involves insulin receptor substrates-1 and -2, activation of phosphatidylinositol 3-kinase and the JAK 2-growth related pathway (1998), Cardiovasc. Res., 40, 96-102.

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.7.1.137	additional information	Rattus norvegicus	insulin signaling in heart involves insulin receptor substrate-1 and insulin receptor substrate-2, activation of phosphatidylinositol 3-kinase	?	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.137	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.137	heart	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.137	ATP + 1-phosphatidylinositol	-	Rattus norvegicus	ADP + phosphatidylinositol 3-phosphate	-	?
2.7.1.137	additional information	insulin signaling in heart involves insulin receptor substrate-1 and insulin receptor substrate-2, activation of phosphatidylinositol 3-kinase	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)