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Literature summary extracted from

  • Le Marchand-Brustel, Y.; Heydrick, S.J.; Jullien, D.; Gautier, N.; Van Obberghen, E.
    Effect of insulin and insulin-like growth factor-I on glucose transport and its transporters in soleus muscle of lean and obese mice (1995), Metab. Clin. Exp., 44, 18-23.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.137 additional information PI3-kinase is activated by insulin and IGF-I in a rapid and transient manner in incubated soleus muscles Mus musculus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.137 Wortmannin
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.137 additional information Mus musculus enzyme could be involved in stimulated glucose transport in muscle ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.137 Mus musculus
-
 lean and obese animals
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidylinositol
-
 Mus musculus ADP + phosphatidylinositol 3-phosphate
-
 ?
2.7.1.137 additional information enzyme could be involved in stimulated glucose transport in muscle Mus musculus ?
-
 ?