Literature summary extracted from

Krymskaya, V.P.; Hoffman, R.; Eszterhas, A.; Kane, S.; Ciocca, V.; Panettieri, R.A., Jr.
EGF activates ErbB-2 and stimulates phosphatidylinositol 3-kinase in human airway smooth muscle cells (1999), Am. J. Physiol., 276, L246-L255.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.1.137	additional information	EGF stimulates phosphatidylinositol 3-kinase in human airway smooth muscle cells	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.137	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.137	muscle	airway smooth muscle cells	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.137	ATP + 1-phosphatidylinositol	-	Homo sapiens	ADP + phosphatidylinositol 3-phosphate	-	?

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Release 2023.1 (January 2023)