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Literature summary extracted from

  • Herrera-Velit, P.; Reiner, N.E.
    Bacterial lipopolysaccharide induces the association and coordinate activation of p53/56lyn and phosphatidylinositol 3-kinase in human monocytes (1996), J. Immunol., 156, 1157-1165.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.1.137 additional information Homo sapiens monocytes respond to LPS with the rapid activation of PI 3-kinase, resulting in transient increases in levels of PtdIns 3,4,5-P3. This process is CD14 dependent and involves the physiological association of PI 3-kinase with activated p53/56lyn ?
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Organism

EC Number Organism UniProt Comment Textmining
2.7.1.137 Homo sapiens
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.137 monocyte
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 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.137 ATP + 1-phosphatidylinositol
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 Homo sapiens ADP + phosphatidylinositol 3-phosphate
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 ?
2.7.1.137 additional information monocytes respond to LPS with the rapid activation of PI 3-kinase, resulting in transient increases in levels of PtdIns 3,4,5-P3. This process is CD14 dependent and involves the physiological association of PI 3-kinase with activated p53/56lyn Homo sapiens ?
-
 ?