Literature summary extracted from

Chakravorty, A.; Joslyn, M.I.; Davis, J.S.
Characterization of insulin and insulin-like growth factor-I actions in the bovine luteal cell: Regulation of receptor tyrosine kinase activity, phosphatidylinositol 3-kinase, and deoxyribonucleic acid synthesis (1993), Endocrinology, 133, 1331-1340.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
2.7.1.137	additional information	insulin and IGF-I treatment increases phosphatidylinositol 3-kinase activity 4.5fold in aPY20 immunoprecipitation from whole cell lysates	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.7.1.137	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.7.1.137	corpus luteum	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.7.1.137	ATP + 1-phosphatidylinositol	-	Bos taurus	ADP + phosphatidylinositol 3-phosphate	-	?

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Release 2023.1 (January 2023)