EC Number | Cloned (Comment) | Organism |
---|---|---|
2.7.1.137 | expression of the 110000 Da subunit in Sf9 insect cells and in COS-1 cells | Bos taurus |
2.7.1.137 | p110 expressed in insect cells possesses Pl3-kinase activity and associates with p85 alpha into an active p85 alpha-p110 complex that binds the activated colony-stimulating factor 1 receptor. p110 expressed in COS-1 cells is catalytically active only when complexed with p85 alpha | Bos taurus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.7.1.137 | 85000 | - |
1 * 85000 + 1 * 110000 | Bos taurus |
2.7.1.137 | 85000 | - |
1 * 85000 + 1 * 124000, deduced from nucleotide sequence | Bos taurus |
2.7.1.137 | 110000 | - |
1 * 85000 + 1 * 110000 | Bos taurus |
2.7.1.137 | 124000 | - |
1 * 85000 + 1 * 124000, deduced from nucleotide sequence | Bos taurus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.7.1.137 | Bos taurus | - |
- |
- |
2.7.1.137 | Bos taurus | P32871 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.7.1.137 | brain | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.7.1.137 | ATP + 1-phosphatidylinositol | - |
Bos taurus | ADP + phosphatidylinositol 3-phosphate | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.7.1.137 | dimer | 1 * 85000 + 1 * 110000 | Bos taurus |
2.7.1.137 | dimer | 1 * 85000 + 1 * 124000, deduced from nucleotide sequence | Bos taurus |