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Literature summary extracted from

  • Mohamed, A.H.; Huang, W.Y.; Huang, W.; Venkatachalam, K.V.; Wakil, S.J.
    Isolation and characterization of a novel acetyl-CoA carboxylase kinase from rat liver (1994), J. Biol. Chem., 269, 6859-6865.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.27 AMP no effect Rattus norvegicus
2.7.11.27 CoA no effect Rattus norvegicus
2.7.11.27 additional information cAMP independent Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.27 citrate
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.11.27 0.0003
-
 acetyl-CoA carboxylase
-
 Rattus norvegicus
2.7.11.27 0.03
-
 ATP
-
 Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.27 40000
-
 SDS-PAGE Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.27 ATP + [acetyl-CoA carboxylase] Rattus norvegicus acetyl-CoA carboxylase bound kinase involved in regulation in vivo ADP + [acetyl-CoA carboxylase] phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.27 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.27
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.27 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.27 ATP + acetyl-CoA carboxylase
-
 Rattus norvegicus ADP + phosphorylated acetyl-CoA carboxylase
-
 ?
2.7.11.27 ATP + [acetyl-CoA carboxylase] phosphorylates Ser77 and Ser1200 Rattus norvegicus ADP + [acetyl-CoA carboxylase] phosphate
-
 ?
2.7.11.27 ATP + [acetyl-CoA carboxylase] inactivation of carboxylase Rattus norvegicus ADP + [acetyl-CoA carboxylase] phosphate
-
 ?
2.7.11.27 ATP + [acetyl-CoA carboxylase] acetyl-CoA carboxylase bound kinase involved in regulation in vivo Rattus norvegicus ADP + [acetyl-CoA carboxylase] phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.27 More high molecular weight aggregates, gel filtration Rattus norvegicus

Synonyms

EC Number Synonyms Comment Organism
2.7.11.27 acetyl-CoA carboxylase bound kinase
-
 Rattus norvegicus