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Literature summary extracted from

  • Mayeenuddin, L.H.; Mitchell, J.
    Squid visual arrestin: cDNA cloning and calcium-dependent phosphorylation by rhodopsin kinase (SQRK) (2003), J. Neurochem., 85, 592-600.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.11.14 membrane also found associated with the rhabdomeric membranes Doryteuthis pealeii 16020
-
2.7.11.14 soluble in the soluble fraction of eye homogenates Doryteuthis pealeii
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.14 Ca2+ Ca2+-dependent phosphorylation of arrestin, Ca2+ concentrations above 0.0025 mM free Ca2+ stimulate, maximal at 0.05 mM Ca2+, Ca2+ may facilitate arrestin-binding to RK, phosphorylation of rhodopsin is not Ca2+-dependent Doryteuthis pealeii
2.7.11.14 Mg2+
-
Doryteuthis pealeii

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.14 ATP + arrestin Doryteuthis pealeii phosphorylation of arrestin in the presence of Ca2+, occurs only after photoactivation in vivo, dual role of RK in the inactivation of the squid visual system ADP + phosphoarrestin
-
?
2.7.11.14 ATP + rhodopsin Doryteuthis pealeii dual role of RK in the inactivation of the squid visual system ADP + phosphorhodopsin
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.14 Doryteuthis pealeii
-
squid
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.14
-
Doryteuthis pealeii

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.14 eye
-
Doryteuthis pealeii
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.14 ATP + arrestin phosphorylation of arrestin in the presence of Ca2+, Ca2+ may facilitate arrestin-binding to RK Doryteuthis pealeii ADP + phosphoarrestin
-
?
2.7.11.14 ATP + arrestin phosphorylation of arrestin in the presence of Ca2+, occurs only after photoactivation in vivo, dual role of RK in the inactivation of the squid visual system Doryteuthis pealeii ADP + phosphoarrestin
-
?
2.7.11.14 ATP + rhodopsin rhodopsin of rhabdomeric membranes Doryteuthis pealeii ADP + phosphorhodopsin
-
?
2.7.11.14 ATP + rhodopsin dual role of RK in the inactivation of the squid visual system Doryteuthis pealeii ADP + phosphorhodopsin
-
?