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Literature summary extracted from

  • Weller, M.; Virmaux, N.; Mandel, P.
    Light-stimulated phosphorylation of rhodopsin in the retina: the presence of a protein kinase that is specific for photobleached rhodopsin (1975), Proc. Natl. Acad. Sci. USA, 72, 381-385.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.11.14 additional information not activated by cAMP Bos taurus
2.7.11.14 additional information not activated by cGMP, dibutyryl-cGMP Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.14 dibutyryl-cAMP weak, not in the dark Bos taurus
2.7.11.14 additional information not inhibited by cAMP; not inhibited by cGMP; not inhibited by dibutyryl-GMP Bos taurus
2.7.11.14 papaverine weak, not in the dark Bos taurus
2.7.11.14 Phosphodiesterase inhibitor SQ 20009 light-dependent Bos taurus
2.7.11.14 theophylline light-dependent Bos taurus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.14 Mg2+ requirement Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.14 ATP + rhodopsin Bos taurus phosphorylation of rhodopsin may control passive permeability to certain ions in rod outer segments, so mediating the responsiveness to a light impulse ADP + phosphorhodopsin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.14 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.11.14 partial Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.14 eye retina Bos taurus
-
2.7.11.14 eye dark-adapted Bos taurus
-
2.7.11.14 retina rod cell outer segment Bos taurus
-
2.7.11.14 retina from dark-adapted eyes Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.7.11.14 0.017
-
 pH 7.4, 37°C Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.14 ATP + rhodopsin phosphorylates bovine rhodopsin Bos taurus ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin highly specific for photobleached rhodopsin Bos taurus ADP + phosphorhodopsin
-
 ?
2.7.11.14 ATP + rhodopsin phosphorylation of rhodopsin may control passive permeability to certain ions in rod outer segments, so mediating the responsiveness to a light impulse Bos taurus ADP + phosphorhodopsin
-
 ?
2.7.11.14 additional information not: unbleached rhodopsin Bos taurus ?
-
 ?
2.7.11.14 additional information not: casein, phosvitin, histones Bos taurus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.11.14 37
-
 assay at Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.11.14 7.4
-
 assay at Bos taurus