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Literature summary extracted from

  • Jinsart, W.; Ternai, B.; Polya, G.M.
    Inhibition and activation of wheat embryo calcium-dependent protein kinase and inhibition of avian myosin light chain kinase by long chain aliphatic amphiphiles (1991), Plant Sci., 78, 165-175.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.18 1,12-diaminododecane IC50: 0.063 mM Gallus gallus
2.7.11.18 1-hexadecylpyridinium bromide IC50: 0.049 mM Gallus gallus
2.7.11.18 acylcarnitin weak Gallus gallus
2.7.11.18 alkylamine long and straight chain, most effective with chain length C-13 to C-18 Gallus gallus
2.7.11.18 alkyltrimethylammonium halide
-
 Gallus gallus
2.7.11.18 D-sphingosine IC50: 0.006 mM Gallus gallus
2.7.11.18 decylamine IC50: 0.2 mM Gallus gallus
2.7.11.18 dihydrosphingosine erythro- and threo-dihydrosphingosine, IC50: 0.008 mM Gallus gallus
2.7.11.18 Dimethyldioctadecylammonium bromide IC50: 0.008 mM Gallus gallus
2.7.11.18 dioctylamine IC50: 0.055 mM Gallus gallus
2.7.11.18 dodecylamine IC50: 0.083 mM Gallus gallus
2.7.11.18 dodecyltrimethylammonium bromide IC50: 0.078 mM Gallus gallus
2.7.11.18 hexadecylamine IC50: 0.016 mM Gallus gallus
2.7.11.18 hexadecyltrimethylammonium bromide IC50: 0.011 mM Gallus gallus
2.7.11.18 lauroylcholine iodide IC50: 0.12 mM Gallus gallus
2.7.11.18 merocyanine dye (C16) IC50: 0.040 mM Gallus gallus
2.7.11.18 merocyanine dye (CH3)
-
 Gallus gallus
2.7.11.18 myristoylcarnitine chloride
-
 Gallus gallus
2.7.11.18 myristoylcholine iodide IC50: 0.02 mM Gallus gallus
2.7.11.18 N-Alkyl-N,N-dimethyl-3-ammonio-1-propanesulfonates zwittergents 3-14 and 16 Gallus gallus
2.7.11.18 N-methyloctadecylamine IC50: 0.01 mM Gallus gallus
2.7.11.18 Octadecylamine IC50: 0.011 mM Gallus gallus
2.7.11.18 oleylamine IC50: 0.006 mM Gallus gallus
2.7.11.18 palmitoylcarnitine chloride
-
 Gallus gallus
2.7.11.18 palmitoylcholine iodide IC50: 0.014 mM Gallus gallus
2.7.11.18 sodium alkylsulfate
-
 Gallus gallus
2.7.11.18 sodium dodecylsulfate IC50: 0.049 mM Gallus gallus
2.7.11.18 Sodium octadecylsulfate IC50: 0.043 mM Gallus gallus
2.7.11.18 Sodium tetradecylsulfate IC50: 0.038 mM Gallus gallus
2.7.11.18 stearoylcarnitine chloride
-
 Gallus gallus
2.7.11.18 stearoylcholine iodide IC50: 0.013 mM Gallus gallus
2.7.11.18 tetradecylamine IC50: 0.012 mM Gallus gallus
2.7.11.18 Tetradecyltrimethylammonium bromide IC50: 0.011 mM Gallus gallus
2.7.11.18 tridecylamine IC50: 0.019 mM Gallus gallus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.18 Ca2+
-
 Gallus gallus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + myosin light chain Gallus gallus
-
 ADP + myosin light chain phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Gallus gallus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + myosin light chain
-
 Gallus gallus ADP + myosin light chain phosphate
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.18 Calmodulin requirement Gallus gallus

IC50 Value

EC Number IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
2.7.11.18 0.006
-
 IC50: 0.006 mM Gallus gallus D-sphingosine
2.7.11.18 0.006
-
 IC50: 0.006 mM Gallus gallus oleylamine
2.7.11.18 0.008
-
 IC50: 0.008 mM Gallus gallus Dimethyldioctadecylammonium bromide
2.7.11.18 0.008
-
 erythro- and threo-dihydrosphingosine, IC50: 0.008 mM Gallus gallus dihydrosphingosine
2.7.11.18 0.01
-
 IC50: 0.01 mM Gallus gallus N-methyloctadecylamine
2.7.11.18 0.011
-
 IC50: 0.011 mM Gallus gallus hexadecyltrimethylammonium bromide
2.7.11.18 0.011
-
 IC50: 0.011 mM Gallus gallus Tetradecyltrimethylammonium bromide
2.7.11.18 0.011
-
 IC50: 0.011 mM Gallus gallus Octadecylamine
2.7.11.18 0.012
-
 IC50: 0.012 mM Gallus gallus tetradecylamine
2.7.11.18 0.013
-
 IC50: 0.013 mM Gallus gallus stearoylcholine iodide
2.7.11.18 0.014
-
 IC50: 0.014 mM Gallus gallus palmitoylcholine iodide
2.7.11.18 0.016
-
 IC50: 0.016 mM Gallus gallus hexadecylamine
2.7.11.18 0.019
-
 IC50: 0.019 mM Gallus gallus tridecylamine
2.7.11.18 0.02
-
 IC50: 0.02 mM Gallus gallus myristoylcholine iodide
2.7.11.18 0.038
-
 IC50: 0.038 mM Gallus gallus Sodium tetradecylsulfate
2.7.11.18 0.04
-
 IC50: 0.040 mM Gallus gallus merocyanine dye (C16)
2.7.11.18 0.043
-
 IC50: 0.043 mM Gallus gallus Sodium octadecylsulfate
2.7.11.18 0.049
-
 IC50: 0.049 mM Gallus gallus sodium dodecylsulfate
2.7.11.18 0.049
-
 IC50: 0.049 mM Gallus gallus 1-hexadecylpyridinium bromide
2.7.11.18 0.055
-
 IC50: 0.055 mM Gallus gallus dioctylamine
2.7.11.18 0.063
-
 IC50: 0.063 mM Gallus gallus 1,12-diaminododecane
2.7.11.18 0.078
-
 IC50: 0.078 mM Gallus gallus dodecyltrimethylammonium bromide
2.7.11.18 0.083
-
 IC50: 0.083 mM Gallus gallus dodecylamine
2.7.11.18 0.12
-
 IC50: 0.12 mM Gallus gallus lauroylcholine iodide
2.7.11.18 0.2
-
 IC50: 0.2 mM Gallus gallus decylamine