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Literature summary extracted from

  • Bailin, G.
    Structure and function of a calmodulin-dependent smooth muscle myosin light chain kinase (1984), Experientia, 40, 1185-1188.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.11.18 naphthalene sulfonamide derivatives
-
 Bos taurus
2.7.11.18 naphthalene sulfonamide derivatives
-
 Gallus gallus
2.7.11.18 naphthalene sulfonamide derivatives
-
 Meleagris gallopavo
2.7.11.18 naphthalene sulfonamide derivatives
-
 Oryctolagus cuniculus
2.7.11.18 phosphorylation at 2 sites Bos taurus
2.7.11.18 phosphorylation at 2 sites Gallus gallus
2.7.11.18 phosphorylation at 2 sites Meleagris gallopavo
2.7.11.18 phosphorylation at 2 sites Oryctolagus cuniculus
2.7.11.18 Trifluoperazine
-
 Bos taurus
2.7.11.18 Trifluoperazine
-
 Gallus gallus
2.7.11.18 Trifluoperazine
-
 Meleagris gallopavo
2.7.11.18 Trifluoperazine
-
 Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.18 Ca2+
-
 Gallus gallus
2.7.11.18 Ca2+
-
 Meleagris gallopavo
2.7.11.18 Ca2+
-
 Bos taurus
2.7.11.18 Ca2+
-
 Oryctolagus cuniculus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.7.11.18 additional information
-
-
 Gallus gallus
2.7.11.18 additional information
-
-
 Meleagris gallopavo
2.7.11.18 additional information
-
-
 Bos taurus
2.7.11.18 additional information
-
-
 Oryctolagus cuniculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.7.11.18 ATP + myosin light chain Gallus gallus
-
 ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain Meleagris gallopavo
-
 ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain Bos taurus
-
 ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain Oryctolagus cuniculus
-
 ADP + myosin light chain phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.18 Bos taurus
-
-
-
2.7.11.18 Gallus gallus
-
-
-
2.7.11.18 Meleagris gallopavo
-
-
-
2.7.11.18 Oryctolagus cuniculus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.11.18 gizzard
-
 Gallus gallus
-
2.7.11.18 gizzard
-
 Meleagris gallopavo
-
2.7.11.18 smooth muscle
-
 Gallus gallus
-
2.7.11.18 smooth muscle
-
 Meleagris gallopavo
-
2.7.11.18 smooth muscle
-
 Bos taurus
-
2.7.11.18 smooth muscle
-
 Oryctolagus cuniculus
-
2.7.11.18 stomach
-
 Gallus gallus
-
2.7.11.18 stomach
-
 Meleagris gallopavo
-
2.7.11.18 stomach
-
 Bos taurus
-
2.7.11.18 stomach
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.11.18 ATP + myosin light chain
-
 Gallus gallus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain
-
 Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain
-
 Bos taurus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain
-
 Oryctolagus cuniculus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle myosin Gallus gallus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle myosin Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle myosin Bos taurus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle myosin Oryctolagus cuniculus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is casein Gallus gallus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is casein Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is casein Bos taurus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is casein Oryctolagus cuniculus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Gallus gallus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Bos taurus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain acceptor substrates are myosin light chains of smooth muscle Oryctolagus cuniculus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Gallus gallus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Meleagris gallopavo ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Bos taurus ADP + myosin light chain phosphate
-
 ?
2.7.11.18 ATP + myosin light chain no substrate is phosphorylase b Oryctolagus cuniculus ADP + myosin light chain phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.7.11.18 More skeletal muscle enzyme structure: overall asymmetric shape, globular head and tail region Gallus gallus
2.7.11.18 More skeletal muscle enzyme structure: overall asymmetric shape, globular head and tail region Meleagris gallopavo
2.7.11.18 More skeletal muscle enzyme structure: overall asymmetric shape, globular head and tail region Bos taurus
2.7.11.18 More skeletal muscle enzyme structure: overall asymmetric shape, globular head and tail region Oryctolagus cuniculus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.11.18 7.8 8
-
 Gallus gallus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.18 Calmodulin requirement Gallus gallus
2.7.11.18 Calmodulin requirement Meleagris gallopavo
2.7.11.18 Calmodulin requirement Bos taurus
2.7.11.18 Calmodulin requirement Oryctolagus cuniculus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Gallus gallus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Meleagris gallopavo
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Bos taurus
2.7.11.18 Calmodulin trypsin or chymotrypsin digested smooth muscle enzyme is independent of Ca2+/calmodulin Oryctolagus cuniculus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Gallus gallus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Meleagris gallopavo
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Bos taurus
2.7.11.18 Calmodulin 1:1 stoichiometric complex in the presence of Ca2+ Oryctolagus cuniculus