BRENDA - Enzyme Database

Dolichol kinase in rat sarcoplasmic reticulum membrane preparations

Itami, T.; Mueck, R.L.; Keenan, R.W.; Biochim. Biophys. Acta 960, 374-381 (1988)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.1.108
Triton X-100
-
Rattus norvegicus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.1.108
ATP
-
Rattus norvegicus
2.7.1.108
GTP
-
Rattus norvegicus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.1.108
0.023
-
dolichol
pH 7.4, 37°C
Rattus norvegicus
2.7.1.108
1.5
-
CTP
pH 7.4, 37°C, skeletal muscle enzyme
Rattus norvegicus
Localization
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.1.108
membrane
-
Rattus norvegicus
16020
-
2.7.1.108
microsome
-
Rattus norvegicus
-
-
2.7.1.108
sarcoplasmic reticulum
-
Rattus norvegicus
16529
-
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.1.108
Ca2+
activated almost equally well by Ca2+, Zn2+ or Mg2+
Rattus norvegicus
2.7.1.108
Mg2+
activated almost equally well by Ca2+, Zn2+ or Mg2+
Rattus norvegicus
2.7.1.108
additional information
skeletal muscle kinase is not activated by Mn2+
Rattus norvegicus
2.7.1.108
Zn2+
-
Rattus norvegicus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.1.108
CTP + dolichol
Rattus norvegicus
-
CDP + dolichyl phosphate
-
Rattus norvegicus
?
2.7.1.108
CTP + dolichol
Rattus norvegicus Sprague-Dawley
-
CDP + dolichyl phosphate
-
Rattus norvegicus Sprague-Dawley
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.7.1.108
Rattus norvegicus
-
Sprague-Dawley
-
2.7.1.108
Rattus norvegicus Sprague-Dawley
-
Sprague-Dawley
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.1.108
brain
-
Rattus norvegicus
-
2.7.1.108
liver
-
Rattus norvegicus
-
2.7.1.108
muscle
leg muscle
Rattus norvegicus
-
2.7.1.108
skeletal muscle
-
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.108
CTP + dolichol
-
640399
Rattus norvegicus
CDP + dolichyl phosphate
-
640399
Rattus norvegicus
?
2.7.1.108
CTP + dolichol
-
640399
Rattus norvegicus Sprague-Dawley
CDP + dolichyl phosphate
-
640399
Rattus norvegicus Sprague-Dawley
?
2.7.1.108
additional information
requires CTP as phosphoryl donor
640399
Rattus norvegicus
?
-
-
-
-
2.7.1.108
additional information
requires CTP as phosphoryl donor
640399
Rattus norvegicus Sprague-Dawley
?
-
-
-
-
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.1.108
7.4
7.7
-
Rattus norvegicus
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
2.7.1.108
Triton X-100
-
Rattus norvegicus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.7.1.108
ATP
-
Rattus norvegicus
2.7.1.108
GTP
-
Rattus norvegicus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.7.1.108
0.023
-
dolichol
pH 7.4, 37°C
Rattus norvegicus
2.7.1.108
1.5
-
CTP
pH 7.4, 37°C, skeletal muscle enzyme
Rattus norvegicus
Localization (protein specific)
EC Number
Localization
Commentary
Organism
GeneOntology No.
Textmining
2.7.1.108
membrane
-
Rattus norvegicus
16020
-
2.7.1.108
microsome
-
Rattus norvegicus
-
-
2.7.1.108
sarcoplasmic reticulum
-
Rattus norvegicus
16529
-
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
2.7.1.108
Ca2+
activated almost equally well by Ca2+, Zn2+ or Mg2+
Rattus norvegicus
2.7.1.108
Mg2+
activated almost equally well by Ca2+, Zn2+ or Mg2+
Rattus norvegicus
2.7.1.108
additional information
skeletal muscle kinase is not activated by Mn2+
Rattus norvegicus
2.7.1.108
Zn2+
-
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.7.1.108
CTP + dolichol
Rattus norvegicus
-
CDP + dolichyl phosphate
-
Rattus norvegicus
?
2.7.1.108
CTP + dolichol
Rattus norvegicus Sprague-Dawley
-
CDP + dolichyl phosphate
-
Rattus norvegicus Sprague-Dawley
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.7.1.108
brain
-
Rattus norvegicus
-
2.7.1.108
liver
-
Rattus norvegicus
-
2.7.1.108
muscle
leg muscle
Rattus norvegicus
-
2.7.1.108
skeletal muscle
-
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.7.1.108
CTP + dolichol
-
640399
Rattus norvegicus
CDP + dolichyl phosphate
-
640399
Rattus norvegicus
?
2.7.1.108
CTP + dolichol
-
640399
Rattus norvegicus Sprague-Dawley
CDP + dolichyl phosphate
-
640399
Rattus norvegicus Sprague-Dawley
?
2.7.1.108
additional information
requires CTP as phosphoryl donor
640399
Rattus norvegicus
?
-
-
-
-
2.7.1.108
additional information
requires CTP as phosphoryl donor
640399
Rattus norvegicus Sprague-Dawley
?
-
-
-
-
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.7.1.108
7.4
7.7
-
Rattus norvegicus