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Literature summary extracted from

  • Walter, R.D.; Osikovski, E.; Albiez, E.J.
    Dolichol kinase in Ascaris suum and Onchocerca volvulus (1985), Mol. Biochem. Parasitol., 14, 211-217.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.7.1.108 Triton X-100
-
 Ascaris suum
2.7.1.108 Triton X-100
-
 Onchocerca volvulus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.108 CDP
-
 Ascaris suum
2.7.1.108 CDP
-
 Onchocerca volvulus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.108 additional information
-
 additional information Km for dolichol 0.0075 mg/ml Ascaris suum
2.7.1.108 additional information
-
 additional information Km for dolichol 0.009 mg/ml Onchocerca volvulus
2.7.1.108 0.75
-
 CTP pH 7.4, 37°C Onchocerca volvulus
2.7.1.108 0.85
-
 CTP pH 7.4, 37°C Ascaris suum

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.108 microsome
-
 Ascaris suum
-
-
2.7.1.108 microsome
-
 Onchocerca volvulus
-
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.108 Ca2+ less effective Ascaris suum
2.7.1.108 Ca2+ less effective Onchocerca volvulus
2.7.1.108 Mg2+ enzyme is dependent on divalent cations Ascaris suum
2.7.1.108 Mg2+ enzyme is dependent on divalent cations Onchocerca volvulus
2.7.1.108 Mn2+ less effective Ascaris suum
2.7.1.108 Mn2+ less effective Onchocerca volvulus

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.108 Ascaris suum
-
-
-
2.7.1.108 Onchocerca volvulus
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.108 CTP + dolichol
-
 Ascaris suum CDP + dolichyl phosphate
-
 ?
2.7.1.108 CTP + dolichol
-
 Onchocerca volvulus CDP + dolichyl phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.108 30 37
-
 Ascaris suum
2.7.1.108 30 37
-
 Onchocerca volvulus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.108 7.4
-
-
 Ascaris suum
2.7.1.108 7.4
-
-
 Onchocerca volvulus