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Literature summary extracted from

  • Badola, P.; Sanders, C.R.2nd.
    Escherichia coli diacylglycerol kinase is an evolutionarily optimized membrane enzyme and catalyzes direct phosphoryl transfer (1997), J. Biol. Chem., 272, 24176-24182.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.107 adenosine 5'-tetraphosphoryl-3-O-(1,2-dihexanoyl)-sn-glycerol
-
 Escherichia coli

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.7.1.107 1
-
 ADP about, pH 6.8, 30°C, reaction with sn-2,3-dihexanoylglycerol Escherichia coli
2.7.1.107 2.6
-
 ATP pH 6.8, 30°C, reaction with sn-2,3-dihexanoylglycerol Escherichia coli
2.7.1.107 4.2
-
 2'-deoxy-ATP pH 6.8, 30°C, reaction with sn-2,3-dihexanoylglycerol Escherichia coli
2.7.1.107 5.9
-
 ITP pH 6.8, 30°C, reaction with sn-2,3-dihexanoylglycerol Escherichia coli
2.7.1.107 8.7
-
 GTP pH 6.8, 30°C, reaction with sn-2,3-dihexanoylglycerol Escherichia coli

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.107 membrane
-
 Escherichia coli 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.107 Escherichia coli
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.107
-
 Escherichia coli

Reaction

EC Number Reaction Comment Organism Reaction ID
2.7.1.107 ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate random equilibrium mechanism Escherichia coli
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.107 2'-deoxy-ATP + sn-1,2-dihexanoylglycerol
-
 Escherichia coli 2'-deoxy-ADP + sn-1,2-dihexanoylglycerol 3-phosphate
-
 ?
2.7.1.107 ADP + sn-1,2-dihexanoylglycerol MgADP- is a very poor phosphoryl donor Escherichia coli AMP + sn-1,2-dihexanoylglycerol 3-phosphate
-
 ?
2.7.1.107 ATP + sn-1,2-dihexanoylglycerol
-
 Escherichia coli ADP + sn-1,2-dihexanoylglycerol 3-phosphate
-
 ?
2.7.1.107 GTP + sn-1,2-dihexanoylglycerol
-
 Escherichia coli GDP + sn-1,2-dihexanoylglycerol 3-phosphate
-
 ?
2.7.1.107 ITP + sn-1,2-dihexanoylglycerol
-
 Escherichia coli IDP + sn-1,2-dihexanoylglycerol 3-phosphate
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.7.1.107 additional information
-
 additional information Ki-value for adenosine 5'-tetraphosphoryl-3-O-(1,2-dihexanoyl)-sn-glycerol is 0.036 mol% Escherichia coli