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Literature summary extracted from

  • Sallach, H.J.
    Formation of serine from hydroxypyruvate and L-alanine (1956), J. Biol. Chem., 223, 1101-1108.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.51 L-alanine + 3-hydroxypyruvate Canis lupus familiaris
-
 pyruvate + L-serine
-
 r
2.6.1.51 L-serine + pyruvate Canis lupus familiaris
-
 3-hydroxypyruvate + L-alanine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.51 Canis lupus familiaris
-
 dog
-
2.6.1.51 Neurospora crassa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.51 kidney
-
 Canis lupus familiaris
-
2.6.1.51 liver
-
 Canis lupus familiaris
-

Storage Stability

EC Number Storage Stability Organism
2.6.1.51 5°C, acetone powder of fresh liver stored in a vacuum desiccator over aluminia retains its enzymatic activity for months Canis lupus familiaris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.51 glutamic acid + 3-hydroxypyruvate
-
 Canis lupus familiaris 2-oxo-1,5-pentandioate + serine
-
 r
2.6.1.51 glycine + 3-hydroxypyruvate
-
 Canis lupus familiaris glyoxylate + L-serine
-
 r
2.6.1.51 glycine + 3-hydroxypyruvate
-
 Canis lupus familiaris L-serine + glyoxylate
-
 r
2.6.1.51 L-alanine + 3-hydroxypyruvate
-
 Neurospora crassa pyruvate + L-serine
-
 r
2.6.1.51 L-alanine + 3-hydroxypyruvate
-
 Canis lupus familiaris pyruvate + L-serine
-
 r
2.6.1.51 L-serine + pyruvate
-
 Canis lupus familiaris 3-hydroxypyruvate + L-alanine
-
 r
2.6.1.51 additional information D-alanine is no substrate Canis lupus familiaris ?
-
 ?

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.51 pyridoxal 5'-phosphate
-
 Canis lupus familiaris