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Literature summary extracted from

  • Lombardo, M.E.; Araujo, L.S.; Batlle, A.
    5-Aminolevulinic acid synthesis in epimastigotes of Trypanosoma cruzi (2003), Int. J. Biochem. Cell Biol., 35, 1263-1271.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.6.1.43 medicine target for chemotherapy against Chagas disease or American trypanosomiasis Trypanosoma cruzi

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.43 L-alanine + 4,5-dioxopentanoate Trypanosoma cruzi
-
 5-aminolevulinate + pyruvate
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.43 Trypanosoma cruzi
-
 Tulahuen strain, Tul 2 stock
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.43 epimastigote
-
 Trypanosoma cruzi
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.43 L-alanine + 4,5-dioxopentanoate
-
 Trypanosoma cruzi 5-aminolevulinate + pyruvate
-
 ir

Synonyms

EC Number Synonyms Comment Organism
2.6.1.43 DOVA-T
-
 Trypanosoma cruzi