BRENDA - Enzyme Database show

Production of delta-aminolevulinic acid: characterization of murine liver 4,5-dioxovaleric acid: L-alanine aminotransferase

McKinney, C.E.; Ades, I.Z.; Int. J. Biochem. 23, 803-810 (1991)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
2.6.1.43
5-aminolevulinate
-
Mus musculus
2.6.1.43
beta-chloroalanine
-
Mus musculus
2.6.1.43
gabaculine
-
Mus musculus
2.6.1.43
glyoxylic acid
-
Mus musculus
2.6.1.43
hemin
-
Mus musculus
2.6.1.43
methylglyoxal
-
Mus musculus
2.6.1.43
pyruvate
-
Mus musculus
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.6.1.43
0.22
-
4,5-Dioxopentanoate
-
Mus musculus
2.6.1.43
0.97
-
L-alanine
-
Mus musculus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.6.1.43
L-alanine + 4,5-dioxopentanoate
Mus musculus
-
5-aminolevulinate + pyruvate
-
Mus musculus
ir
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.6.1.43
Mus musculus
-
mouse
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.6.1.43
hepatocyte
-
Mus musculus
-
2.6.1.43
liver
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.6.1.43
L-alanine + 4,5-dioxopentanoate
-
640059
Mus musculus
5-aminolevulinate + pyruvate
-
640059
Mus musculus
ir
pH Optimum
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.6.1.43
7
8
-
Mus musculus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
2.6.1.43
5-aminolevulinate
-
Mus musculus
2.6.1.43
beta-chloroalanine
-
Mus musculus
2.6.1.43
gabaculine
-
Mus musculus
2.6.1.43
glyoxylic acid
-
Mus musculus
2.6.1.43
hemin
-
Mus musculus
2.6.1.43
methylglyoxal
-
Mus musculus
2.6.1.43
pyruvate
-
Mus musculus
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
2.6.1.43
0.22
-
4,5-Dioxopentanoate
-
Mus musculus
2.6.1.43
0.97
-
L-alanine
-
Mus musculus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.6.1.43
L-alanine + 4,5-dioxopentanoate
Mus musculus
-
5-aminolevulinate + pyruvate
-
Mus musculus
ir
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.6.1.43
hepatocyte
-
Mus musculus
-
2.6.1.43
liver
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.6.1.43
L-alanine + 4,5-dioxopentanoate
-
640059
Mus musculus
5-aminolevulinate + pyruvate
-
640059
Mus musculus
ir
pH Optimum (protein specific)
EC Number
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
2.6.1.43
7
8
-
Mus musculus