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Literature summary extracted from

  • Bonfils, J.; Faure, M.; Gibrat, J.F.; Glomot, F.; Papet, I.
    Sheep cytosolic branched-chain amino acid aminotransferase: cDNA cloning, primary structure and molecular modelling and its unique expression in muscles (2000), Biochim. Biophys. Acta, 1494, 129-136.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.42
-
 Ovis aries
2.6.1.42 cytosolic enzyme, cDNA Ovis aries

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.42 cytosol
-
 Ovis aries 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.42 43070
-
 BCATc, calculated from amino acid sequence Ovis aries

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.42 L-isoleucine + 2-oxoglutarate Ovis aries
-
 3-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-leucine + 2-oxoglutarate Ovis aries
-
 4-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-valine + 2-oxoglutarate Ovis aries
-
 3-methyl-2-oxobutanoate + L-glutamate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.42 Ovis aries
-
 sheep
-
2.6.1.42 Ovis aries O97932 sheep, BCATm cDNA
-
2.6.1.42 Ovis aries Q9GKM4 sheep, BCATm cDNA
-
2.6.1.42 Ovis aries Q9GKM4 sheep, BCATc amino acid sequence
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.42 brain
-
 Ovis aries
-
2.6.1.42 placenta
-
 Ovis aries
-
2.6.1.42 skeletal muscle
-
 Ovis aries
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.42 L-isoleucine + 2-oxoglutarate
-
 Ovis aries 3-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-leucine + 2-oxoglutarate
-
 Ovis aries 4-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-valine + 2-oxoglutarate
-
 Ovis aries 3-methyl-2-oxobutanoate + L-glutamate
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.42 pyridoxal 5'-phosphate BCATc Ovis aries