Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Schadewaldt, P.; Wendel, U.; Hammen, H.W.
    Human branched-chain L-amino acid aminotransferase: activity and subcellular localization in cultured skin fibroblasts (1995), Amino Acids, 9, 147-160.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.6.1.42 cytosol
-
Homo sapiens 5829
-
2.6.1.42 mitochondrion
-
Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.42 L-leucine + 2-oxoglutarate Homo sapiens
-
4-methyl-2-oxopentanoate + L-glutamate
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.42 Homo sapiens
-
human
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.42 fibroblast
-
Homo sapiens
-
2.6.1.42 skin
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.42 L-2-aminobutyrate + 2-oxoglutarate
-
Homo sapiens 2-oxobutanoate + L-glutamate
-
r
2.6.1.42 L-2-aminobutyrate + 4-methyl-2-oxopentanoate
-
Homo sapiens 2-oxobutanoate + L-leucine
-
r
2.6.1.42 L-alanine + 2-oxoglutarate
-
Homo sapiens 2-oxopropanoate + L-glutamate
-
r
2.6.1.42 L-alanine + 4-methyl-2-oxopentanoate
-
Homo sapiens pyruvate + L-leucine
-
r
2.6.1.42 L-allo-isoleucine + 2-oxobutyrate
-
Homo sapiens 3-methyl-2-oxopentanoate + 2-aminobutyrate
-
r
2.6.1.42 L-allo-isoleucine + 2-oxohexanoate
-
Homo sapiens 3-methyl-2-oxopentanoate + 2-aminohexanoate
-
r
2.6.1.42 L-allo-isoleucine + 2-oxoisohexanoate
-
Homo sapiens 3-methyl-2-oxopentanoate + L-leucine
-
r
2.6.1.42 L-allo-isoleucine + 2-oxoisopentanoate
-
Homo sapiens 3-methyl-2-oxopentanoate + L-valine
-
r
2.6.1.42 L-allo-isoleucine + 2-oxooctanoate
-
Homo sapiens 3-methyl-2-oxopentanoate + 2-aminooctanoate
-
r
2.6.1.42 L-aspartate + 2-oxoglutarate
-
Homo sapiens oxaloacetate + L-glutamate
-
r
2.6.1.42 L-glutamate + 2-oxoglutarate
-
Homo sapiens 2-oxoglutarate + L-glutamate
-
r
2.6.1.42 L-glutamate + 4-methyl-2-oxopentanoate
-
Homo sapiens 2-oxoglutarate + L-leucine
-
r
2.6.1.42 L-isoleucine + 2-oxo-isopentanoate
-
Homo sapiens 2-oxoisohexanoate + L-valine
-
r
2.6.1.42 L-isoleucine + 2-oxobutyrate
-
Homo sapiens 2-oxoisohexanoate + 2-aminobutyrate
-
r
2.6.1.42 L-isoleucine + 2-oxohexanoate
-
Homo sapiens L-norleucine + 2-oxoisohexanoate
-
r
2.6.1.42 L-isoleucine + 2-oxoisohexanoate
-
Homo sapiens 3-methyl-2-oxopentanoate + L-leucine
-
r
2.6.1.42 L-isoleucine + 2-oxooctanoate
-
Homo sapiens 2-oxoisohexanoate + 2-aminooctanoate
-
r
2.6.1.42 L-leucine + 2-oxo-butyrate
-
Homo sapiens 2-oxoisohexanoate + 2-aminobutyrate
-
r
2.6.1.42 L-leucine + 2-oxoglutarate
-
Homo sapiens 4-methyl-2-oxopentanoate + L-glutamate
-
?
2.6.1.42 L-leucine + 2-oxoglutarate
-
Homo sapiens 4-methyl-2-oxopentanoate + L-glutamate
-
r
2.6.1.42 L-leucine + 2-oxohexanoate
-
Homo sapiens 2-oxoisohexanoate + 2-aminohexanoate
-
r
2.6.1.42 L-leucine + 2-oxoisohexanoate
-
Homo sapiens 2-oxoisohexanoate + L-leucine
-
r
2.6.1.42 L-leucine + 2-oxooctanoate
-
Homo sapiens 2-oxoisohexanoate + 2-aminooctanoate
-
r
2.6.1.42 L-leucine + 3-methyl-2-oxobutanoate
-
Homo sapiens 4-methyl-2-oxopentanoate + L-valine
-
r
2.6.1.42 L-leucine + 3-methyl-2-oxopentanoate
-
Homo sapiens 2-oxo-4-methylpentanoate + L-isoleucine
-
r
2.6.1.42 L-leucine + p-hydroxyphenylpyruvate
-
Homo sapiens 2-oxoisohexanoate + L-tyrosine
-
r
2.6.1.42 L-leucine + phenylpyruvate
-
Homo sapiens 2-oxoisohexanoate + L-phenylalanine
-
r
2.6.1.42 L-leucine + pyruvate slight activity Homo sapiens 2-oxoisohexanoate + L-alanine
-
r
2.6.1.42 L-norleucine + 4-methyl-2-oxopentanoate
-
Homo sapiens 2-oxohexanoate + L-leucine
-
r
2.6.1.42 L-norvaline + 4-methyl-2-oxopentanoate
-
Homo sapiens 2-oxopentanoate + L-leucine
-
r
2.6.1.42 L-valine + 2-oxobutyrate
-
Homo sapiens 2-oxoisopentanoate + 2-aminobutanoate
-
r
2.6.1.42 L-valine + 2-oxohexanoate
-
Homo sapiens 2-oxoisopentanoate + 2-aminohexanoate
-
r
2.6.1.42 L-valine + 2-oxooctanoate
-
Homo sapiens 2-oxoisopentanoate + 2-aminooctanoate
-
r
2.6.1.42 L-valine + 4-methyl-2-oxopentanoate
-
Homo sapiens 2-oxoisopentanoate + L-leucine
-
r
2.6.1.42 additional information transamination activity with oxaloacetate is too low to be evaluated, DL-aminoadipate, glycine, L-phenylalanine, L-tyrosine and L-methionine are no substrates Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
2.6.1.42 BCAA aminotransferase
-
Homo sapiens
2.6.1.42 BCAA-AT
-
Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.42 8.3
-
-
Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.6.1.42 6.5 10
-
Homo sapiens

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.42 pyridoxal 5'-phosphate
-
Homo sapiens