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Literature summary extracted from

  • Feild, M.J.; Nguyen, D.C.; Armstrong, F.B.
    Amino acid sequence of Salmonella typhimurium branched-chain amino acid aminotransferase (1989), Biochemistry, 28, 5306-5310.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.6.1.42 ilvGEDAY gene cluster expressed in Escherichia coli JA199 Salmonella enterica subsp. enterica serovar Typhimurium

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.6.1.42 crystallized from recombinant Escherichia coli Salmonella enterica subsp. enterica serovar Typhimurium

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.42 33920
-
 6 * 33920, calculated from amino acid sequence Salmonella enterica subsp. enterica serovar Typhimurium
2.6.1.42 204900
-
 calculated from amino acid sequence Salmonella enterica subsp. enterica serovar Typhimurium

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.42 L-isoleucine + 2-oxoglutarate Salmonella enterica subsp. enterica serovar Typhimurium biosynthesis of L-isoleucine 3-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-leucine + 2-oxoglutarate Salmonella enterica subsp. enterica serovar Typhimurium biosynthesis of L-leucine 4-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-valine + 2-oxoglutarate Salmonella enterica subsp. enterica serovar Typhimurium biosynthesis of L-valine 3-methyl-2-oxobutanoate + L-glutamate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.42 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.42
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.42 L-isoleucine + 2-oxoglutarate biosynthesis of L-isoleucine Salmonella enterica subsp. enterica serovar Typhimurium 3-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-leucine + 2-oxoglutarate biosynthesis of L-leucine Salmonella enterica subsp. enterica serovar Typhimurium 4-methyl-2-oxopentanoate + L-glutamate
-
 r
2.6.1.42 L-valine + 2-oxoglutarate biosynthesis of L-valine Salmonella enterica subsp. enterica serovar Typhimurium 3-methyl-2-oxobutanoate + L-glutamate
-
 r

Subunits

EC Number Subunits Comment Organism
2.6.1.42 hexamer 6 * 33920, calculated from amino acid sequence Salmonella enterica subsp. enterica serovar Typhimurium

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.42 pyridoxal 5'-phosphate
-
 Salmonella enterica subsp. enterica serovar Typhimurium