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Literature summary extracted from

  • Distler, J.; Kaufman, B.; Roseman, S.
    Enzymic synthesis of a diamino sugar nucleotide by extracts of type XIV Diplococcus pneumoniae (1966), Arch. Biochem. Biophys., 116, 466-478.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.6.1.34 additional information not affected by EDTA Streptococcus pneumoniae
2.6.1.34 pyridoxal 5'-phosphate absolute requirement Streptococcus pneumoniae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.6.1.34 additional information not affected by MgCl2 at 0.01 M Streptococcus pneumoniae

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.34 UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate Streptococcus pneumoniae
-
 UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.34 Streptococcus pneumoniae
-
 type XIV, ATCC 6314
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.34 type XIV, ATCC 6314, partial Streptococcus pneumoniae

Storage Stability

EC Number Storage Stability Organism
2.6.1.34 -15°C, stable for at least 3 weeks Streptococcus pneumoniae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.34 UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate
-
 Streptococcus pneumoniae UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
 r
2.6.1.34 UDP-2-acetamido-4-keto-2,6-dideoxyhexose + L-glutamate glutamate can only partially be replaced by glutamine and cannot be replaced by asparagine and aspartate Streptococcus pneumoniae UDP-2-acetamido-4-amino-2,4,6-trideoxyhexose + 2-oxoglutarate
-
 r

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.34 37
-
 assay at Streptococcus pneumoniae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.34 7.9
-
-
 Streptococcus pneumoniae