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Literature summary extracted from

  • Ellis, D.B.; Sommar, K.M.
    Biosynthesis of respiratory tract musins. II. Control of hexosamine metabolism by L-glutamine D-fructose 6-phosphate aminotransferase (1972), Biochim. Biophys. Acta, 267, 105-112.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.6.1.16 glucose 6-phosphate, 12 mM, required as protective agent during purification Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.16 6-diazo-5-oxo-L-norleucine
-
 Bos taurus
2.6.1.16 UDP-N-acetylglucosamine partial Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.16 0.2
-
 L-glutamine pH 7.4, 37°C Bos taurus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.6.1.16 350000
-
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.16 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.6.1.16 trachea
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.16 L-glutamine + D-fructose 6-phosphate
-
 Bos taurus L-glutamate + D-glucosamine 6-phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.16 37
-
 assay at Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.16 6.5 7.5
-
 Bos taurus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.6.1.16 6 8.5
-
 Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.6.1.16 0.001
-
 6-diazo-5-oxo-L-norleucine pH 7.4, 37°C Bos taurus
2.6.1.16 0.04
-
 UDP-N-acetylglucosamine pH 7.4, 37°C Bos taurus