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Literature summary extracted from

  • Badet, B.; Vermoote, P.; Le Goffic, F.
    Glucosamine synthetase from Escherichia coli: kinetic mechanism and inhibition by N3-fumaroyl-L-2,3-diaminopropionic derivatives (1988), Biochemistry, 27, 2282-2287.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.6.1.16 6-diazo-5-oxo-L-norleucine
-
 Escherichia coli
2.6.1.16 N3-(4-Methoxyfumaroyl)-L-2,3-diaminopropanoic acid
-
 Escherichia coli
2.6.1.16 N3-fumaramoyl-L-2,3-diaminopropanoic acid
-
 Escherichia coli
2.6.1.16 N3-fumaroyl-L-2,3-diaminopropanoic acid
-
 Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.16 Escherichia coli
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.16 L-glutamine + D-fructose 6-phosphate
-
 Escherichia coli L-glutamate + D-glucosamine 6-phosphate
-
 ?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.6.1.16 0.00035
-
 N3-(4-Methoxyfumaroyl)-L-2,3-diaminopropanoic acid pH 7.5, 37°C Escherichia coli
2.6.1.16 0.0014
-
 6-diazo-5-oxo-L-norleucine pH 7.5, 37°C Escherichia coli
2.6.1.16 0.0551
-
 N3-fumaroyl-L-2,3-diaminopropanoic acid pH 7.5, 37°C Escherichia coli