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Literature summary extracted from

  • Bracher, M.; Schweingruber, M.E.
    Purification of the tyrosine inhibitable 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Schizosaccharomyces pombe (1977), Biochim. Biophys. Acta, 485, 446-451.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.5.1.54 Tyr at pH 6.2-7.8; Tyr-sensitive isozyme Schizosaccharomyces pombe

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.5.1.54 Co2+ no stimulation of purified enzyme Schizosaccharomyces pombe

Organism

EC Number Organism UniProt Comment Textmining
2.5.1.54 Schizosaccharomyces pombe
-
 tyrosine-sensitive isozyme
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.5.1.54 326fold Schizosaccharomyces pombe

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.5.1.54 10.75
-
 purified enzyme Schizosaccharomyces pombe

Storage Stability

EC Number Storage Stability Organism
2.5.1.54 0.1 M potassium phosphate, pH 7.4, 1 mM phosphoenolpyruvate, 0.02% NaN3, purified enzyme, stable for 2-3 months Schizosaccharomyces pombe

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.5.1.54 phosphoenolpyruvate + D-erythrose 4-phosphate + H2O
-
 Schizosaccharomyces pombe 2-dehydro-3-deoxy-D-arabino-heptonate 7-phosphate + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.5.1.54 dimer
-
 Schizosaccharomyces pombe

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.5.1.54 6.2 7.8
-
 Schizosaccharomyces pombe