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Literature summary extracted from

  • Basu, M.; Basu, S.
    Enzymatic synthesis of a tetraglycosylceramide by a galactosyltransferase from rabbit bone marrow (1972), J. Biol. Chem., 247, 1489-1495.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.86 EDTA complete inhibition Oryctolagus cuniculus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.86 0.12
-
 UDPgalactose
-
 Oryctolagus cuniculus
2.4.1.86 0.5
-
 N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
-
 Oryctolagus cuniculus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.86 Cd2+ 6-7% of the activity with Mn2+ Oryctolagus cuniculus
2.4.1.86 Co2+ 6-7% of the activity with Mn2+ Oryctolagus cuniculus
2.4.1.86 Mg2+ 6-7% of activity with Mn2+ Oryctolagus cuniculus
2.4.1.86 Mn2+ required Oryctolagus cuniculus

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.86 Oryctolagus cuniculus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.86 partial Oryctolagus cuniculus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.86 bone marrow
-
 Oryctolagus cuniculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.86 additional information UDPglucose cannot substitute for UDPgalactose, Tay-Sachs ganglioside (GM2) is a poor galactose acceptor Oryctolagus cuniculus ?
-
 ?
2.4.1.86 UDPgalactose + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
-
 Oryctolagus cuniculus UDP + 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.86 6.4
-
-
 Oryctolagus cuniculus