Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Jezequel-Cuer, M.; N'Guyen-Cong, H.; Biou, D.; Durand, G.
    Oligosaccharide specificity of normal human hepatocyte alpha1-3 fucosyltransferase (1993), Biochim. Biophys. Acta, 1157, 252-258.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.152 GDP-choline 0.5 mM, 90% inhibition Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.152 0.0065
-
 GDP-fucose pH 7.2, 37°C Homo sapiens
2.4.1.152 0.38
-
 alpha(2,3) bisialylated biantennary glycan pH 7.2, 37°C Homo sapiens
2.4.1.152 0.65
-
 3'-sialyl N-acetyl lactosamine pH 7.2, 37°C Homo sapiens
2.4.1.152 0.74
-
 unsialylated biantennary glycan pH 7.2, 37°C Homo sapiens
2.4.1.152 2.6
-
 N-acetyl lactosamine pH 7.2, 37°C Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.4.1.152 Golgi vesicle
-
 Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.4.1.152 additional information Homo sapiens the hepatocellular enzyme is involved in the synthesis of sialosyl LeX determinants on cirrhotic alpha1AGP ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.152 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.152 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.152 hepatocyte
-
 Homo sapiens
-
2.4.1.152 liver
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.152 0.000002
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.152 GDP-beta-L-fucose + alpha(2,3) bisialylated biantennary glycan
-
 Homo sapiens ?
-
 ?
2.4.1.152 GDP-beta-L-fucose + unsialylated biantennary glycan
-
 Homo sapiens ?
-
 ?
2.4.1.152 GDP-L-fucose + 3'-sialyl N-acetyl lactosamine
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + asialotransferrin
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)Glc
-
 Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
2.4.1.152 GDP-L-fucose + Galbeta(1,4)GlcNAc i.e. N-acetyllactosamine Homo sapiens GDP + Galbeta(1,4)(Fucalpha(1,3))GlcNAc
-
 ?
2.4.1.152 GDP-L-fucose + lactose weak activity Homo sapiens GDP + ?
-
 ?
2.4.1.152 additional information the hepatocellular enzyme is involved in the synthesis of sialosyl LeX determinants on cirrhotic alpha1AGP Homo sapiens ?
-
 ?