EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.4.1.152 | diethyldicarbonate | IC50: 0.092. Preincubation at 23°C gives maximal inhibition, 75%, after 180 s. Preincubation at 13°C gives 55% inhibition after 3 min. Preincubation at 4°C results in only 35% inhibition | Homo sapiens | |
2.4.1.152 | dithionitrobenzene | - |
Homo sapiens | |
2.4.1.152 | N-bromosuccinimide | moderate inhibition | Homo sapiens | |
2.4.1.152 | NEM | 50% inhibition at 0.1 mM, complete inhibition at 0.5 mM. At 37°C complete inhibition is reached after 3 min. At 23°C more than 10 min are required to reach maximal activity. No inactivation after 10 min at 4°C | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.4.1.152 | Homo sapiens | - |
recombinant enzyme expressed in Sf-9 cells via baculovirus infection | - |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.4.1.152 | additional information | recombinant enzyme expressed in Sf-9 cells via baculovirus infection | Homo sapiens | - |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
2.4.1.152 | 0.092 | - |
IC50: 0.092 mM. Preincubation at 23°C gives maximal inhibition, 75%, after 180 s. Preincubation at 13°C gives 55% inhibition after 3 min. Preincubation at 4°C results in only 35% inhibition | Homo sapiens | diethyldicarbonate |