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Literature summary extracted from

  • Prieels, J.P.; Beyers, T.; Hill, R.L.
    Human milk fucosyltransferase (1977), Biochem. Soc. Trans., 5, 838-839.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.152 0.062
-
 GDP-L-fucose pH 7.6, 15 mM MnCl2 Homo sapiens
2.4.1.152 1.4
-
 6-deoxy-alpha-L-galactopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->3)-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranose pH 7.6, 15 mM MnCl2, 0.095 mM GDP-fucose Homo sapiens
2.4.1.152 5
-
 lacto-N-tetraose pH 7.6, 15 mM MnCl2, 0.095 mM GDP-fucose Homo sapiens
2.4.1.152 17
-
 Gal-beta-(1->3)-[Fuc-alpha-(1->4)-])GlcNAc-beta-(1->3)-Gal-beta-(1->4)-Glc pH 7.6, 15 mM MnCl2, 0.095 mM GDP-fucose Homo sapiens
2.4.1.152 20
-
 Fucalpha(1,2)Galbeta(1,4)Glc pH 7.6, 15 mM MnCl2, 0.095 mM GDP-fucose Homo sapiens
2.4.1.152 83
-
 lactose pH 7.6, 15 mM MnCl2, 0.095 mM GDP-fucose Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.152 Mn2+ required Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.152 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.152
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.152 milk
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.152 GDP-L-fucose + Fucalpha(1,2)Galbeta(1,4)Glc
-
 Homo sapiens GDP + Fucalpha(1,2)Galbeta(1,4)(Fucalpha(1,3))Glc
-
 ?
2.4.1.152 GDP-L-fucose + lacto-N-fucopentaose I
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + lacto-N-fucopentaose II
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + lacto-N-tetraose
-
 Homo sapiens GDP + ?
-
 ?
2.4.1.152 GDP-L-fucose + lactose
-
 Homo sapiens GDP + ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.152 7.6 8
-
 Homo sapiens