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Literature summary extracted from

  • Sigal, E.; Grunberger, D.; Cashman, J.R.; Craik, C.S.; Caughey, G.H.; Nadel, J.A.
    Arachidonate 15-lipoxygenase from human eosinophil-enriched leukocytes: partial purification and properties (1988), Biochem. Biophys. Res. Commun., 150, 376-383.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.13.11.33 phosphatidylcholine stimulates Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
1.13.11.33 ATP
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.13.11.33 0.068
-
 arachidonic acid
-
 Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
1.13.11.33 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
1.13.11.33 partial Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.13.11.33 eosinophil 15-lipoxygenase activity is 100fold greater in eosinophils than in neutrophils Homo sapiens
-
1.13.11.33 leukocyte eosinophil-enriched leukocytes Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.13.11.33 2.125
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.13.11.33 arachidonate + O2
-
 Homo sapiens (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyeicosa-5,8,11,13-tetraenoate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.13.11.33 7 8.5
-
 Homo sapiens