Literature summary extracted from

Kakinuma, K.; Ozawa, K.; Fujimoto, Y.; Akutsu, N.; Oshima, T.
Stereochemistry of the decarboxylation reaction catalysed by 3-isopropylmalate dehydrogenase from the thermophilic bacterium Thermus thermophilus (1989), J. Chem. Soc. Chem. Commun., 1989, 1190-1192.

No PubMed abstract available

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.1.1.85	Thermus thermophilus	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.1.1.85	(2R,3S)-3-isopropylmalate + NAD+	decarboxylation appears to take place with retention of configuration	Thermus thermophilus	2-oxoisocaproate + NADH + H+ + CO2	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
1.1.1.85	NAD+	-	Thermus thermophilus

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Release 2023.1 (January 2023)