Literature summary extracted from

Mitsui, K.i.; Teraoka, H.; Tsukada, K.
Complete purification and immunochemical analysis of S-adenosylmethionine synthetase from bovine brain (1988), J. Biol. Chem., 263, 11211-11216.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.5.1.6	tripolyphosphate	-	Bos taurus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.5.1.6	0.01	-	L-methionine	-	Bos taurus
2.5.1.6	0.05	-	ATP	-	Bos taurus

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
2.5.1.6	Mg2+	-	Bos taurus

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
2.5.1.6	38000	-	x * 48000 + x * 38000, SDS-PAGE	Bos taurus
2.5.1.6	48000	-	x * 48000 + x * 38000, SDS-PAGE	Bos taurus
2.5.1.6	160000	-	gel filtration	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.6	Bos taurus	-	bovine	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.5.1.6	partial	Bos taurus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.5.1.6	brain	-	Bos taurus	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.5.1.6	12.4	-	-	Bos taurus

Storage Stability

EC Number	Storage Stability	Organism
2.5.1.6	2°C, stable for at least 2 months	Bos taurus

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.6	2'-deoxy-ATP + L-methionine + H2O	-	Bos taurus	?	-	?
2.5.1.6	3'-deoxy-ATP + L-methionine + H2O	-	Bos taurus	?	-	?
2.5.1.6	ATP + L-methionine + H2O	-	Bos taurus	S-adenosyl-L-methionine + phosphate + diphosphate	-	?

Subunits

EC Number	Subunits	Comment	Organism
2.5.1.6	?	x * 48000 + x * 38000, SDS-PAGE	Bos taurus

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Release 2023.1 (January 2023)